Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21863298 | 0.81 | HTT (0.45) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6646719 | 0.74 | ALDH1A1 (0.57) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20976770 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL20976773 | 0.73 | WDR5 (0.50) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL70391 | 0.69 | MYC (0.70) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30481735 | 0.69 | MYC (0.70) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6120419 | 0.69 | ALDH1A1 (0.50) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6207135 | 0.68 | ALDH1A1 (0.49) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4941467 | 0.68 | POLB (0.49) | MYCALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20976801 | 0.68 | GABRP (0.39) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3093291-B1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-05-08 | — | — | EP | disclosed |