SCHEMBL2097737

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2095174	0.93	HPGD (0.72)	HPGDPOLBCA12CA1CA2
	SCHEMBL971083	0.82	HPGD (1.00)	HPGDPOLBCA12CA1CA2
	SCHEMBL644199	0.82	HPGD (0.92)	HPGDPOLBCA12CA1CA2
	SCHEMBL2095786	0.81	HSD11B1 (0.58)	HPGDPOLBCA12CA1CA2
	SCHEMBL2092237	0.81	ALDH1A1 (0.64)	HPGDPOLBCA12CA1CA2
	SCHEMBL2091419	0.81	ALDH1A1 (0.65)	HPGDLMNAALDH1A1MGLLHSD11B1
	SCHEMBL2091763	0.81	HPGD (0.52)	HPGDPOLBL3MBTL3L3MBTL1ALDH1A1
	SCHEMBL396945	0.81	HPGD (0.66)	HPGDPOLBCA12CA1CA2
	SCHEMBL5137	0.81	CYP3A4 (0.54)	HPGDPOLBLMNAALDH1A1KMT2A
	SCHEMBL24185725	0.81	HPGD (0.96)	HPGDPOLBCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.