Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20980507 | 0.83 | TGFBR1 (0.43) | TGFBR1TGFBR2HTR2CHTR2AFLT1 | |
| SCHEMBL25712784 | 0.79 | DYRK1A (0.36) | TGFBR1TGFBR2DYRK1AKEAP1 | |
| SCHEMBL20980469 | 0.78 | KDM4E (0.44) | TGFBR1NPC1RAB9ASMN1; SMN2AXL | |
| SCHEMBL20980510 | 0.75 | CYP11B2 (0.35) | HTR2CMC4R | |
| SCHEMBL1104802 | 0.68 | DYRK1A (0.45) | TGFBR1TGFBR2CDK8ROCK1DYRK1A | |
| SCHEMBL25712761 | 0.67 | TGFBR1 (0.35) | TGFBR1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21084240 | 0.64 | TGFBR1 (0.60) | TGFBR1TGFBR2 | |
| SCHEMBL20980451 | 0.64 | BRD4 (0.42) | TGFBR1HTR2CHTR2AMC4RFLT1 | |
| SCHEMBL24160899 | 0.63 | DRD1 (0.41) | TGFBR1TGFBR2HTR2CHTR2ABRD4 | |
| SCHEMBL5486071 | 0.63 | HTR2C (0.66) | HTR2CHTR2ABRD4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214587-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-01-04 | — | — | US | disclosed |
| US-20190135843-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11214587-B2 | Organic electroluminescent materials and devices | OCIAD1, OCIAD2, OPRD1 | TGFBR1 4705/4885TGFBR2 4769/4885HTR2C 802/4885 |
| US-20190135843-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, OPRD1 | TGFBR1 4705/4885TGFBR2 4769/4885HTR2C 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.