Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15909593 | 0.79 | NPC1 (0.44) | DYRK1AKEAP1TGFBR1MEN1CYP1A2 | |
| SCHEMBL21530593 | 0.75 | KDM4E (0.50) | DYRK1AKEAP1TGFBR1MEN1CYP1A2 | |
| SCHEMBL21161402 | 0.70 | RAB9A (0.51) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29605597 | 0.68 | AHR (0.48) | KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8642940 | 0.68 | DNMT1 (0.40) | MAPK9MAPK10KDRSMN1; SMN2RET | |
| SCHEMBL9611716 | 0.68 | CYP1A2 (0.41) | CYP1A2KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL268000 | 0.67 | — | — | |
| SCHEMBL7883 | 0.67 | — | — | |
| SCHEMBL21593291 | 0.67 | LTA4H (0.41) | FAAHKDRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24231953 | 0.67 | TGFBR1 (0.43) | DYRK1AKEAP1TGFBR1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12022728-B2 | Organic electroluminescent element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-20230002419-A1 | NOVEL BORON COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME | SFC CO., LTD. (KR) | 2023-01-05 | — | — | US | disclosed |
| US-11482676-B2 | Light emitting diode including boron compound | SFC CO., LTD. (KR) | 2022-10-25 | — | — | US | disclosed |
| US-20210036233-A1 | LIGHT EMITTING DIODE INCLUDING BORON COMPOUND | SFC CO., LTD. (KR) | 2021-02-04 | — | — | US | disclosed |
| US-10763442-B2 | Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20070232618-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-10-04 | — | — | US | disclosed |
| US-7271180-B2 | 1-Aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-09-18 | — | — | US | disclosed |
| US-7259165-B2 | Heterocyclyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-08-21 | — | — | US | disclosed |
| US-7238696-B2 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-07-03 | — | — | US | disclosed |
| US-7220756-B2 | N-sulfonylheterocyclopyrrolyl-alkylamine compounds as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-05-22 | — | — | US | disclosed |
| WO-2007032833-A1 | AZINYL-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-03-22 | — | — | WO | disclosed |
| US-20070054896-A1 | Serotonin (5-HT6) receptor ligands such as 3-(1-naphthylsulfonyl)-5-(piperidin-4-yloxy)-1H-indazole, used for the treatment nervous sytem disorders such as attention deficit disorder, anxiety, epilepsy, depression, schizophrenia, obsessive compulsive, sleep, eating and neurodegenerative disorders | WYETH (US) | 2007-03-08 | — | — | US | disclosed |
| WO-2007021711-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070037802-A1 | such as N,N-Dimethyl-3-{[3-(1-naphthylsulfonyl)-1H-indazol-5-yl]oxy}propan-1-amine, used for the treatment of a central nervous system disorders | WYETH (US) | 2007-02-15 | — | — | US | disclosed |
| US-20040167122-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | WYETH | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232618-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | HTR6, HTR2C, HTR3B | DYRK1A 2349/4885KEAP1 1712/4885TGFBR1 2739/4885 |
| US-20230002419-A1 | NOVEL BORON COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME | CLTB, CD79B, RB1 | DYRK1A 1747/4885KEAP1 1684/4885TGFBR1 2568/4885 |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | DYRK1A 3876/4885KEAP1 1306/4885TGFBR1 741/4885 |
| US-20070037802-A1 | such as N,N-Dimethyl-3-{[3-(1-naphthylsulfonyl)-1H-indazol-5-yl]oxy}propan-1-amine, used for the treatment of a central nervous system disorders | HTR6, TPH1, HTR1A | DYRK1A 1900/4885KEAP1 1420/4885TGFBR1 3212/4885 |
| US-20040167122-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | HTR6, HTR1A, HTR2C | DYRK1A 2522/4885KEAP1 1549/4885TGFBR1 2191/4885 |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | BCL6B, BRD7, DBF4 | DYRK1A 263/4885KEAP1 1557/4885TGFBR1 4581/4885 |
| US-10763442-B2 | Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device | OR10J3, RER1, L1CAM | DYRK1A 4428/4885KEAP1 1842/4885TGFBR1 2804/4885 |
| US-12022728-B2 | Organic electroluminescent element and electronic device | L1CAM, ESR1, LEF1 | DYRK1A 4125/4885KEAP1 693/4885TGFBR1 1313/4885 |
| US-20070054896-A1 | Serotonin (5-HT6) receptor ligands such as 3-(1-naphthylsulfonyl)-5-(piperidin-4-yloxy)-1H-indazole, used for the treatment nervous sytem disorders such as attention deficit disorder, anxiety, epilepsy, depression, schizophrenia, obsessive compulsive, sleep, eating and neurodegenerative disorders | HTR6, HTR1A, HTR3B | DYRK1A 2047/4885KEAP1 1078/4885TGFBR1 3531/4885 |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | DDC, TYR, AOC2 | DYRK1A 2568/4885KEAP1 494/4885TGFBR1 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.