Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | STAT5B | P51692 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327847 | 0.87 | STAT5B (0.49) | TAS2R14STAT5BF2ALDH1A1POLB | |
| SCHEMBL14327849 | 0.86 | STAT5B (0.48) | TAS2R14STAT5BF2ALDH1A1POLB | |
| SCHEMBL14327848 | 0.81 | STAT5B (0.44) | BMP1PTGER1STAT5BF2CA12 | |
| SCHEMBL3398503 | 0.80 | BMP1 (0.52) | BMP1TAS2R14PTGER1AOC3L3MBTL1 | |
| SCHEMBL7067656 | 0.79 | STAT5B (0.44) | TAS2R14STAT5BF2ALDH1A1POLB | |
| SCHEMBL14328707 | 0.78 | PSEN1 (0.40) | TAS2R14STAT5BPOLBCA12CA1 | |
| SCHEMBL6926342 | 0.78 | CA1 (0.45) | BMP1STAT5BF2ALDH1A1CA12 | |
| SCHEMBL3397090 | 0.78 | ALDH1A1 (0.62) | BMP1TAS2R14ALDH1A1CA12CA1 | |
| SCHEMBL3010321 | 0.77 | AOC3 (0.56) | AOC3 | |
| SCHEMBL7063146 | 0.77 | STAT5B (0.47) | BMP1TAS2R14STAT5BL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995056-B2 | Direct C—H amination and aza-annulation | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-05-04 | — | — | US | disclosed |
| US-20190152892-A1 | DIRECT C-H AMINATION AND AZA-ANNULATION | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995056-B2 | Direct C—H amination and aza-annulation | AOC3, ALKBH3, AZI2 | BMP1 1807/4885TAS2R14 3984/4885PTGER1 4756/4885 |
| US-20190152892-A1 | DIRECT C-H AMINATION AND AZA-ANNULATION | AOC3, ALKBH3, AZI2 | BMP1 1835/4885TAS2R14 3955/4885PTGER1 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.