SCHEMBL20984530

SCHEMBL20984530

O=P(O)(O)NNc1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.52
CA12 O43570 3/20 0.52
MMP9 P14780 2/20 0.52
MMP8 P22894 2/20 0.52
MMP14 P50281 2/20 0.52
GAA P10253 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA14 Q9ULX7 3/20 0.43
CA9 Q16790 2/20 0.43
CA2 P00918 1/20 0.43
IDO1 P14902 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28856291 0.78 MMP2 (0.52) MMP2CA12MMP9MMP8MMP14
SCHEMBL20985042 0.78 CA12 (0.52) MMP2CA12GAAKDM4EALDH1A1
SCHEMBL28045561 0.78 PTGS2 (0.52) MMP2MMP9MMP8MMP14GAA
SCHEMBL20984210 0.77 ALDH1A1 (0.50) CA12MMP8MMP14GAASMN1; SMN2
SCHEMBL2693735 0.77 MMP2 (0.55) MMP2CA12MMP9MMP8MMP14
SCHEMBL20984950 0.76 CA1 (0.57) MMP2GAASMN1; SMN2KDM4EALDH1A1
SCHEMBL20984418 0.74 PTGS2 (0.51) GAASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL20984499 0.74 ALDH1A1 (0.42) ALDH1A1TDP1MAOB
SCHEMBL20984638 0.74 CA1 (0.56) MMP2CA12CA2NPC1RAB9A
SCHEMBL20984611 0.74 SRC (0.56) GAASMN1; SMN2ALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US claimed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 CN claimed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US claimed
CN-105272872-A 4-bromophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN claimed
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US disclosed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 CN disclosed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US disclosed
CN-105272872-A 4-bromophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN disclosed
CN-105272872-A 4-bromophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN disclosed
CN-105272872-A 4-bromophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts HPD, TYR, PDK2 MMP2 2339/4885CA12 1659/4885MMP9 3460/4885
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts HPD, TYR, PDK2 MMP2 2339/4885CA12 1659/4885MMP9 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.