Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 6/20 | 0.50 |
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27660361 | 0.91 | TSHR (0.61) | ALDH1A1CES2CES1DAOTSHR | |
| Benzoic Acid SCHEMBL27458611 | 0.87 | CES2 (0.55) | CES2CES1TSHRHTTKMT2A | |
| Benzoic Acid SCHEMBL28328412 | 0.86 | CES2 (0.56) | ALDH1A1CES2CES1DAOTSHR | |
| Terephthalic Acid SCHEMBL20767681 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL7678291 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CES2CES1TSHRPRSS1 | |
| SCHEMBL7678289 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CES2CES1TSHRPRSS1 | |
| Benzoic Acid SCHEMBL27950835 | 0.83 | CES2 (0.45) | ALDH1A1CES2CES1DAOTSHR | |
| SCHEMBL266279 | 0.81 | LMNA (0.56) | ALDH1A1CES2CES1TSHRPRSS1 | |
| Benzoic Acid SCHEMBL27867681 | 0.81 | TSHR (0.54) | ALDH1A1CES2CES1DAOTSHR | |
| Hydrogen Peroxide SCHEMBL29219018 | 0.81 | LMNA (0.56) | ALDH1A1CES2CES1TSHRPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174373-B2 | Resin composition and resin molded body | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20190153200-A1 | RESIN COMPOSITION AND RESIN MOLDED BODY | FUJI XEROX CO., LTD. (JP) | 2019-05-23 | — | — | US | disclosed |