Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986858 | 0.87 | ALDH1A1 (0.56) | PREPFKBP1AMEN1KMT2AALDH1A1 | |
| SCHEMBL22829603 | 0.85 | FKBP1A (0.51) | PREPDPP4DPP7FKBP1AALDH1A1 | |
| SCHEMBL7300040 | 0.84 | PREP (0.51) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL3272148 | 0.80 | PREP (0.45) | PREPFKBP1AMEN1KMT2AKEAP1 | |
| SCHEMBL25174200 | 0.78 | PREP (0.55) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL22541566 | 0.78 | GAA (0.56) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL21522762 | 0.77 | ALDH1A1 (0.48) | DPP4DPP7FKBP1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1938766 | 0.76 | HTT (0.48) | PREPFKBP1AMEN1KMT2AKEAP1 | |
| SCHEMBL31420576 | 0.76 | PRCP (0.58) | FKBP1AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL25186706 | 0.75 | PREP (0.57) | PREPDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190152992-A1 | BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ORION CORPORATION (FI) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152992-A1 | BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE | TBXA2R, ADRA2C, ADRB2 | PREP 3897/4885DPP4 3277/4885DPP8 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.