Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561178 | 0.98 | HTR2A (0.38) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6732026 | 0.96 | HTR2A (0.37) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6732020 | 0.96 | HTR2A (0.37) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6295599 | 0.96 | HTR2A (0.37) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6295601 | 0.96 | HTR2A (0.37) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| SCHEMBL8679648 | 0.82 | GPR3 (0.33) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| SCHEMBL7627897 | 0.82 | ACHE (0.34) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| SCHEMBL7152500 | 0.81 | GPR3 (0.32) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6295671 | 0.80 | GPR3 (0.32) | HTR2AGPR3ACHEADRA1ACHRM2 | |
| Hydrochloric Acid SCHEMBL6727342 | 0.80 | CYP3A4 (0.34) | HTR2AGPR3ACHEADRA1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190153135-A1 | Activator Compositions, Their Preparation, And Their Use In Catalysts | GRACE W R & CO (US) | 2019-05-23 | — | — | US | disclosed |