Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20989033 | 0.87 | SIGMAR1 (0.50) | ALDH1A1KMT2ATSHRKDM4ESMN1; SMN2 | |
| SCHEMBL20988916 | 0.83 | KMT2A (0.48) | ALDH1A1KMT2ATSHRKDM4ELMNA | |
| SCHEMBL20988923 | 0.80 | C3AR1 (0.46) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL27904819 | 0.79 | MLNR (0.66) | FKBP1AALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL10305162 | 0.78 | FKBP1A (0.76) | FKBP1AALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL20988917 | 0.78 | TRPV1 (0.54) | ALDH1A1KMT2ATSHRKDM4EMEN1 | |
| SCHEMBL20989079 | 0.77 | C3AR1 (0.65) | C3AR1 | |
| SCHEMBL2833225 | 0.77 | KMT2A (0.80) | FKBP1AALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL20989095 | 0.77 | FKBP1A (0.59) | FKBP1AALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL20988925 | 0.77 | C3AR1 (0.59) | ALDH1A1POLBC3AR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134056-A1 | K-RAS MUTATIONS AND ANTAGONISTS | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOG (US) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134056-A1 | K-RAS MUTATIONS AND ANTAGONISTS | KRAS, NRAS, HRAS | FKBP1A 3693/4885ALDH1A1 4716/4885KMT2A 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.