SCHEMBL20992134

SCHEMBL20992134

N[C@H]1CCN(CC(F)(F)F)C1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.33
LTA4H P09960 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
HRH2 P25021 2/20 0.31
HRH1 P35367 2/20 0.31
HRH3 Q9Y5N1 1/20 0.31
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13740262 1.00 KDM1A (0.33) KDM1ALTA4HGNAI3GNAO1GNAI1
SCHEMBL22789404 1.00 KDM1A (0.33) KDM1ALTA4HGNAI3GNAO1GNAI1
SCHEMBL12245493 0.88 ADORA2A (0.33) KDM1AADORA2A
SCHEMBL14737759 0.88 ADORA2A (0.33) KDM1AADORA2A
SCHEMBL459481 0.86 GNAI3 (0.39) KDM1AGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL14738232 0.86 ADORA2A (0.32) KDM1AADORA2A
Hydrochloric Acid SCHEMBL2378908 0.86 ADORA2A (0.32) KDM1AADORA2A
Hydrochloric Acid SCHEMBL14738192 0.86 ADORA2A (0.32) KDM1AADORA2A
Hydrochloric Acid SCHEMBL14738190 0.86 ADORA2A (0.32) KDM1AADORA2A
Hydrochloric Acid SCHEMBL16973697 0.84 GNAI3 (0.42) KDM1AGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO INC (US) 2026-03-26 US disclosed
US-10287301-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2019-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF RRM1, RRM2B, RRM2 KDM1A 3197/4885LTA4H 4121/4885GNAI3 4157/4885
US-10287301-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders CFD, F12, F3 KDM1A 4506/4885LTA4H 524/4885GNAI3 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.