SCHEMBL20994292

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19806271	1.00	KLK5 (0.41)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL6908318	0.81	KLK5 (0.44)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL16119293	0.81	KLK5 (0.44)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL16228157	0.81	KLK5 (0.44)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL8909470	0.80	ALDH1A1 (0.46)	KLK5NFKB1NFKB2RELACTSS
	SCHEMBL12091407	0.79	KLK5 (0.43)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL6907174	0.77	KLK5 (0.45)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL16228121	0.77	KLK5 (0.45)	KLK5NFKB1NFKB2RELACTSL
	SCHEMBL21037178	0.76	FNTA (0.35)	—
	SCHEMBL25076194	0.74	CTSL (0.43)	KLK5NFKB1NFKB2RELACTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.