Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20994292 | 0.76 | KLK5 (0.41) | — | |
| SCHEMBL21035864 | 0.72 | TSHR (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11881163 | 0.72 | KDM4E (0.46) | ALDH1A1 | |
| SCHEMBL25076192 | 0.69 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL25474776 | 0.68 | ALDH1A1 (0.36) | ALDH1A1PTGS2 | |
| SCHEMBL21983787 | 0.67 | PTGS2 (0.35) | FNTAPGGT1BALDH1A1PTGS2 | |
| SCHEMBL16351132 | 0.67 | ALDH1A1 (0.38) | FNTAPGGT1BALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL11878599 | 0.67 | ALDH1A1 (0.38) | ALDH1A1PTGS2 | |
| SCHEMBL20622190 | 0.66 | CHRM1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL9629978 | 0.65 | ALDH1A1 (0.34) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489231-B1 | PIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10710988-B2 | Piperazine derivative | ASTELLAS PHARMA INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| US-20190202815-A1 | PIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2019-07-04 | — | — | US | disclosed |
| EP-3489231-A1 | PIPERAZINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10710988-B2 | Piperazine derivative | GPR4, MC4R, TRPC4 | FNTA 1252/4885PGGT1B 2072/4885ALDH1A1 2792/4885 |
| US-20190202815-A1 | PIPERAZINE DERIVATIVE | GPR4, MC4R, TRPC4 | FNTA 1252/4885PGGT1B 2072/4885ALDH1A1 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.