Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995362 | 0.86 | PTGS2 (0.49) | PTGS2EPHB4P2RY14TEKSCN5A | |
| SCHEMBL20995378 | 0.84 | CYP19A1 (0.46) | PTGS2EPHB4TEKCA12CA9 | |
| SCHEMBL20995353 | 0.83 | ALOX5 (0.41) | PTGS2P2RY14KIF11 | |
| SCHEMBL20995384 | 0.83 | NPC1 (0.44) | PTGS2EPHB4TEKCA12CA9 | |
| SCHEMBL20995373 | 0.80 | HSP90AA1 (0.52) | PTGS2SCN5AHSP90AA1HSP90AB1ABCG2 | |
| SCHEMBL20995351 | 0.77 | CYP19A1 (0.42) | PTGS2EPHB4TEKCA12CA9 | |
| SCHEMBL12413911 | 0.76 | EPHB4 (0.54) | PTGS2EPHB4P2RY14TEKSCN5A | |
| SCHEMBL20995347 | 0.74 | FLT3 (0.41) | PTGS2EPHB4TEKCA12CA9 | |
| SCHEMBL12420376 | 0.74 | PTGS2 (0.65) | PTGS2P2RY14CA12CA9KDR | |
| SCHEMBL20995369 | 0.74 | CYP19A1 (0.41) | PTGS2EPHB4TEKCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161452-A1 | Process for the preparation of azidoperfluoroalkanes and N-polyfluoroalkyl azides | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2019-05-30 | — | — | US | claimed |
| US-10590091-B2 | Process for the preparation of azidoperfluoroalkanes and N-polyfluoroalkyl azides | Ustav Organicke Chemie A Biochemie AV CR , v.v.i. (CZ) | 2020-03-17 | — | — | US | disclosed |
| US-20190161452-A1 | Process for the preparation of azidoperfluoroalkanes and N-polyfluoroalkyl azides | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590091-B2 | Process for the preparation of azidoperfluoroalkanes and N-polyfluoroalkyl azides | CYP2F1, PRXL2A, CRBN | PTGS2 3378/4885EPHB4 2987/4885P2RY14 248/4885 |
| US-20190161452-A1 | Process for the preparation of azidoperfluoroalkanes and N-polyfluoroalkyl azides | CYP2F1, PRXL2A, CRBN | PTGS2 3378/4885EPHB4 2987/4885P2RY14 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.