SCHEMBL2273295

SCHEMBL2273295

CN(C)[SiH](c1ccccc1)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.36
SLC6A2 P23975 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
AOC3 Q16853 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269751 0.76 SLC6A2 (0.34) SLC6A2TAAR1AOC3ALDH1A1TSHR
SCHEMBL18398 0.69 MAPK1 (0.36) KCNN4SLC6A2TAAR1ALDH1A1TSHR
SCHEMBL2271915 0.69 ALDH1A1 (0.36) KCNN4TAAR1AOC3ALDH1A1TSHR
SCHEMBL2099548 0.69 ALDH1A1 (0.36) KCNN4TAAR1AOC3ALDH1A1TSHR
SCHEMBL8381893 0.69 ALDH1A1 (0.37) KCNN4SLC6A2TAAR1ALDH1A1TSHR
SCHEMBL3691011 0.69 MAPK1 (0.36) KCNN4SLC6A2TAAR1ALDH1A1TSHR
SCHEMBL2153983 0.67 ALDH1A1 (0.35) KCNN4TAAR1AOC3ALDH1A1TSHR
SCHEMBL1494198 0.67 ALDH1A1 (0.37) SLC6A2TAAR1ALDH1A1TSHRMAPK1
SCHEMBL30367101 0.67 MAPK1 (0.35) SLC6A2TAAR1ALDH1A1TSHRMAPK1
SCHEMBL2267937 0.67 ALDH1A1 (0.35) KCNN4TAAR1AOC3ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed