Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362085 | 0.77 | ALDH1A3 (0.67) | ALDH1A3ALDH3A1ALDH1A1TYRL3MBTL1 | |
| SCHEMBL11521133 | 0.76 | ALDH1A3 (1.00) | ALDH1A3ALDH3A1ALDH1A1TYRL3MBTL1 | |
| SCHEMBL9362042 | 0.76 | ALDH1A3 (0.76) | ALDH1A3ALDH3A1ALDH1A1TYRL3MBTL1 | |
| SCHEMBL27251678 | 0.76 | ALDH1A3 (0.65) | ALDH1A3ALDH3A1ALDH1A1TYRL3MBTL1 | |
| SCHEMBL7995434 | 0.76 | ALDH1A3 (0.65) | ALDH1A3ALDH3A1ALDH1A1L3MBTL1CYP2A6 | |
| SCHEMBL31299763 | 0.76 | ALDH1A3 (0.65) | ALDH1A3ALDH3A1ALDH1A1KDM4EHPGD | |
| SCHEMBL12889911 | 0.75 | CRHR1 (0.43) | ALDH1A3TSHRKDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL9322668 | 0.74 | TYR (0.48) | ALDH1A3ALDH3A1ALDH1A1TYRCYP2A6 | |
| SCHEMBL29818670 | 0.74 | TYR (0.48) | ALDH1A3ALDH1A1TYRCYP2A6MAPT | |
| SCHEMBL9231758 | 0.74 | TYR (0.52) | ALDH1A3ALDH1A1TYRCYP2A6CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163952-B2 | RAR receptor agonist ligands and use thereof in human medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-04-24 | — | — | US | disclosed |
| EP-2146951-B1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RES & DEV (FR) | 2010-12-01 | — | — | EP | disclosed |
| US-20100261754-A1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-10-14 | — | — | US | disclosed |
| EP-2146951-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | Galderma Research & Development (FR) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008152260-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261754-A1 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | RARA, RARB, RARG | ALDH1A3 120/4885ALDH3A1 456/4885ALDH1A1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.