Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261 | 0.89 | NR1H4 (0.41) | GPR119ALDH1A1SMN1; SMN2KDM4EOXTR | |
| SCHEMBL7276526 | 0.87 | GPR119 (0.42) | GPR119ALDH1A1OXTRAVPR1ANR1H4 | |
| SCHEMBL3058 | 0.82 | OXTR (0.41) | GPR119ALDH1A1SMN1; SMN2OXTRAVPR1A | |
| SCHEMBL2099 | 0.79 | LTB4R2 (0.55) | GPR119OXTRAVPR1A | |
| SCHEMBL2100 | 0.79 | LTB4R2 (0.55) | GPR119OXTRAVPR1A | |
| SCHEMBL3537 | 0.78 | MEN1 (0.44) | ALDH1A1SMN1; SMN2KDM4EOXTRAVPR1A | |
| SCHEMBL3536 | 0.78 | MEN1 (0.44) | ALDH1A1SMN1; SMN2KDM4EOXTRAVPR1A | |
| SCHEMBL7278162 | 0.76 | OXTR (0.40) | GPR119ALDH1A1OXTRAVPR1ANR1H4 | |
| SCHEMBL2104 | 0.75 | NLRP3 (0.43) | ALDH1A1SMN1; SMN2KDM4EOXTRAVPR1A | |
| SCHEMBL7280581 | 0.73 | OXTR (0.44) | GPR119OXTRAVPR1ANR1H4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |