Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001945 | 1.00 | GHSR (0.45) | GHSRKMT2AMEN1CHRM2CHRM1 | |
| SCHEMBL21035633 | 1.00 | GHSR (0.45) | GHSRKMT2AMEN1CHRM2CHRM1 | |
| SCHEMBL21035632 | 0.89 | CHRM2 (0.43) | KMT2AMEN1CHRM2CHRM1MMP1 | |
| SCHEMBL21035634 | 0.89 | CHRM2 (0.43) | KMT2AMEN1CHRM2CHRM1MMP1 | |
| SCHEMBL21035630 | 0.87 | CHRM2 (0.42) | KMT2AMEN1CHRM2CHRM1MMP1 | |
| SCHEMBL21035631 | 0.87 | CHRM2 (0.42) | KMT2AMEN1CHRM2CHRM1MMP1 | |
| SCHEMBL21035628 | 0.87 | KMT2A (0.40) | GHSRKMT2AMEN1CHRM2CHRM1 | |
| SCHEMBL21035069 | 0.86 | GHSR (0.48) | GHSRKMT2AMEN1MMP1MMP3 | |
| SCHEMBL21035597 | 0.86 | GHSR (0.48) | GHSRKMT2AMEN1MMP1MMP3 | |
| SCHEMBL21035342 | 0.85 | GHSR (0.47) | GHSRKMT2AMEN1MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |