Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 8/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842151 | 0.76 | ALDH1A1 (0.50) | LTC4SFGFR1FGFR2FGFR3KDR | |
| SCHEMBL25262182 | 0.76 | FGFR1 (0.41) | LTC4SFGFR1FGFR2FGFR3KDR | |
| SCHEMBL18658375 | 0.75 | OPRM1 (0.52) | LTC4SFGFR1FGFR2FGFR3KDR | |
| SCHEMBL29116510 | 0.73 | OPRM1 (0.46) | FGFR1FGFR2FGFR3KDRFGFR4 | |
| SCHEMBL25514117 | 0.73 | LTC4S (0.37) | LTC4SFGFR1FGFR2FGFR3KDR | |
| SCHEMBL5842999 | 0.73 | FGFR1 (0.38) | LTC4SFGFR1FGFR2FGFR3KDR | |
| SCHEMBL25255886 | 0.70 | REN (0.45) | FGFR1FGFR2FGFR3KDRFGFR4 | |
| SCHEMBL295453 | 0.69 | ALDH1A1 (0.48) | USP2ALDH1A1S1PR1 | |
| SCHEMBL26280939 | 0.69 | ALDH1A1 (0.48) | USP2ALDH1A1S1PR1 | |
| SCHEMBL14163838 | 0.69 | ALDH1A1 (0.48) | USP2ALDH1A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3178818-B1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2019-05-22 | — | — | EP | disclosed |