Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309202 | 0.95 | FABP3 (0.52) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL18309199 | 0.93 | FABP3 (0.50) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL18309171 | 0.86 | FABP3 (0.45) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL27744380 | 0.85 | ACE2 (0.46) | FABP3FABP4ACE2RXRACSNK2A1 | |
| SCHEMBL5160469 | 0.84 | FABP3 (0.47) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL18309194 | 0.83 | FABP3 (0.42) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL19826061 | 0.83 | FABP3 (0.42) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL20724874 | 0.81 | GABRP (0.43) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL29077088 | 0.80 | FABP3 (0.44) | FABP3FABP4ACE2ALDH1A1BCL2 | |
| SCHEMBL10136527 | 0.80 | EIF4A3 (0.44) | FABP3FABP4ACE2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190153025-A1 | Dithioamine Reducing Agents | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190153025-A1 | Dithioamine Reducing Agents | TMT1A, QSOX1, TST | FABP3 979/4885FABP4 1681/4885ACE2 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.