SCHEMBL2102084

SCHEMBL2102084

CCC(C)[Si](Cl)(c1ccccc1)N(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
LMNA P02545 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2101679 0.85 PGR (0.33) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL2101028 0.84 AOC3 (0.32) ADRA2BHTR2AHRH1KCNH2LMNA
SCHEMBL2272374 0.78 ADRA2B (0.33) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL2101581 0.78 PGR (0.33) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL1313652 0.75 LMNA (0.35) LMNATRPA1
SCHEMBL2102454 0.75 LMNA (0.35) LMNATRPA1
SCHEMBL1315271 0.75 LMNA (0.35) LMNATRPA1
SCHEMBL2103364 0.74 PGR (0.31) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL1317173 0.73 LMNA (0.34) LMNATRPA1
SCHEMBL2101348 0.72 TP53 (0.33) ADRA2AKCNH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed