Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604867 | 0.82 | HTT (0.62) | TSHRSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL14970814 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL17131918 | 0.72 | KDM4E (0.50) | TSHRSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL14970841 | 0.72 | THRB (0.68) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL18559353 | 0.72 | SMN1; SMN2 (1.00) | TSHRSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL17131975 | 0.67 | HTT (0.53) | TSHRSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL14583724 | 0.64 | TDP1 (0.49) | HPGDMAPTLMNAALDH1A1KDM4E | |
| SCHEMBL28504931 | 0.63 | TLR8 (0.69) | TSHRMAPTHTTLMNAALDH1A1 | |
| SCHEMBL20616717 | 0.63 | KMT2A (0.57) | TSHRSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL4942865 | 0.62 | ALDH1A1 (0.52) | TSHRSMN1; SMN2HPGDMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151289-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) Histone Demethylase | UNIV YALE (US) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151289-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) Histone Demethylase | KDM1A, KDM1B, JMJD1C | TSHR 4563/4885SMN1; SMN2 4161/4885HPGD 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.