Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18146951 | 0.84 | LMNA (0.47) | LMNANPC1RAB9ATP53MAPK10 | |
| SCHEMBL21021576 | 0.82 | LMNA (0.41) | LMNANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21022138 | 0.79 | NPC1 (0.42) | LMNANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21021713 | 0.77 | TGM2 (0.41) | LMNANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21022127 | 0.76 | HTT (0.42) | NPC1RAB9ATP53MAPK10ALDH1A1 | |
| SCHEMBL22401233 | 0.72 | KDM4E (0.49) | LMNAALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL21021091 | 0.71 | MAPT (0.44) | LMNARAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL21021742 | 0.70 | ALDH1A1 (0.41) | LMNANPC1RAB9AALDH1A1IDO1 | |
| SCHEMBL20076473 | 0.69 | KDM4E (0.35) | LMNAALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL27606045 | 0.69 | KDM4E (0.46) | LMNANPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |