SCHEMBL21021576

SCHEMBL21021576

C=C(Nc1ccc(F)cc1)c1cc(N)ccc1F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.41
IDO1 P14902 1/20 0.39
MAOB P27338 2/20 0.38
TGM2 P21980 1/20 0.38
P2RX1 P51575 1/20 0.37
GRM5 P41594 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAOA P21397 1/20 0.36
SNCA P37840 1/20 0.36
RAB9A P51151 3/20 0.35
MAPT P10636 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
GRIK1 P39086 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022138 0.84 NPC1 (0.42) LMNAALDH1A1IDO1MEN1KMT2A
SCHEMBL21021713 0.82 TGM2 (0.41) LMNAALDH1A1IDO1MAOBTGM2
SCHEMBL21021265 0.82 LMNA (0.42) LMNAALDH1A1IDO1TGM2RAB9A
SCHEMBL21022127 0.81 HTT (0.42) ALDH1A1TGM2MEN1KMT2ARAB9A
SCHEMBL21021742 0.81 ALDH1A1 (0.41) LMNAALDH1A1IDO1MAOBTGM2
SCHEMBL18146857 0.81 LMNA (0.61) LMNAALDH1A1P2RX1GRM5MEN1
SCHEMBL21021263 0.76 RAPGEF4 (0.39) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL21020921 0.74 CYP1A2 (0.38) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL20076658 0.71 ALDH1A1 (0.41) LMNAALDH1A1IDO1MAOBTGM2
SCHEMBL28747395 0.71 LMNA (0.61) LMNAALDH1A1P2RX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed