Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277611 | 0.80 | ACHE (0.41) | PTGESACHEMAPTMEN1TP53 | |
| SCHEMBL30715286 | 0.77 | ALDH1A1 (0.45) | ACHEMAPTMEN1TP53KMT2A | |
| SCHEMBL31722528 | 0.77 | TDP1 (0.45) | ACHETP53ALDH1A1TSHRPBRM1 | |
| SCHEMBL31717355 | 0.77 | ACHE (0.39) | PTGESACHEMAPTMEN1TP53 | |
| SCHEMBL21022263 | 0.75 | TDP1 (0.39) | TP53ALKBH3ALDH1A1TSHRRAPGEF4 | |
| SCHEMBL22232130 | 0.74 | TDP1 (0.34) | TP53ALKBH3ALDH1A1RAPGEF4SMN1; SMN2 | |
| SCHEMBL30954963 | 0.73 | CCR1 (0.37) | PTGESKMT2AORAI1 | |
| SCHEMBL170493 | 0.72 | — | — | |
| SCHEMBL13176930 | 0.71 | PLA2G7 (0.50) | PTGESMAPTMEN1TP53KMT2A | |
| SCHEMBL31717375 | 0.70 | TSHR (0.53) | ACHEMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |