Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363376 | 0.82 | TRPA1 (0.50) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL28836502 | 0.80 | CNR2 (0.58) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL21021863 | 0.77 | PTGES (0.43) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL30715287 | 0.77 | CNR2 (0.41) | ALDH1A1MAPTTDP1KDM4ETSHR | |
| SCHEMBL29727907 | 0.77 | ALOX15 (0.47) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL7642852 | 0.76 | TDP1 (0.52) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL13201408 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL27522720 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL12002 | 0.72 | — | — | |
| SCHEMBL13176930 | 0.71 | PLA2G7 (0.50) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478337-B | Axial chiral sulfur-containing diaryl derivative and synthesis method thereof | 安徽泽升科技有限公司上海分公司 | 2023-11-28 | — | — | CN | disclosed |