Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014424 | 0.76 | TSHR (0.52) | NPFFR2MEN1MAPTKMT2ATSHR | |
| SCHEMBL31599679 | 0.76 | TSHR (0.52) | NPFFR2MEN1MAPTKMT2ATSHR | |
| SCHEMBL20042871 | 0.76 | TSHR (0.59) | TP53MEN1POLBMAPTKMT2A | |
| SCHEMBL22878979 | 0.76 | TP53 (0.31) | TP53 | |
| SCHEMBL7982038 | 0.75 | MAOA (0.43) | LMNAHTTMEN1MAPTKMT2A | |
| SCHEMBL20042775 | 0.74 | ALDH1A1 (0.54) | LMNATP53HTTMEN1MAPT | |
| SCHEMBL9274485 | 0.72 | MEN1 (0.38) | NPFFR2MEN1MAPTKMT2ATSHR | |
| SCHEMBL11145835 | 0.72 | HSP90AA1 (0.49) | LMNAESR1NPFFR2TSHR | |
| SCHEMBL30482512 | 0.72 | MEN1 (0.38) | NPFFR2MEN1MAPTKMT2ATSHR | |
| SCHEMBL6128400 | 0.72 | CYP3A4 (0.45) | LMNAMEN1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |