SCHEMBL21022303

SCHEMBL21022303

CCc1ccc(C2C(c3ccc(CC(C)(C)F)c(O)c3)C2(Cl)Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
SLC9A1 P19634 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
TRPA1 O75762 1/20 0.31
ADRB2 P07550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021767 0.76 LMNA (0.34) SLC9A1
SCHEMBL21022153 0.69 KDM1A (0.34) KDM1ASLC9A1MEN1MAPTKMT2A
SCHEMBL20076857 0.68 IDH1 (0.33) KDM1A
SCHEMBL20076432 0.67 MEN1 (0.40) MEN1MAPTKMT2A
SCHEMBL21022128 0.66 RXRA (0.33)
SCHEMBL21029939 0.64 SLC5A2 (0.37) SLC9A1MAPTTRPA1
SCHEMBL20076684 0.63 SLC9A1 (0.38) SLC9A1KMT2A
SCHEMBL21021657 0.62 KDM1A (0.41) KDM1AMEN1MAPTKMT2A
SCHEMBL21021542 0.62 SLC9A1 (0.37) SLC9A1
SCHEMBL21020918 0.62 SLC5A2 (0.35) SLC9A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed