Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456499 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HTTL3MBTL1RECQLTDP1 | |
| SCHEMBL11088115 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HTTTP53RECQLNPSR1 | |
| SCHEMBL11084826 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HTTL3MBTL1TP53KDM4E | |
| SCHEMBL14262278 | 0.83 | CXCR3 (0.45) | CREBBPALDH1A1L3MBTL1TP53NPSR1 | |
| SCHEMBL21022863 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HTTL3MBTL1TDP1CYP1A2 | |
| SCHEMBL21022668 | 0.81 | CYP3A4 (0.49) | ALDH1A1HTTL3MBTL1RECQLTDP1 | |
| SCHEMBL11082445 | 0.80 | HTT (0.70) | ALDH1A1HTTL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL11079506 | 0.79 | KDM4E (0.55) | ALDH1A1HTTL3MBTL1TP53KDM4E | |
| SCHEMBL11782096 | 0.77 | DRD2 (0.48) | ALDH1A1HTTL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL11514777 | 0.76 | ALDH1A1 (0.71) | CREBBPALDH1A1CXCR3KDM4ETNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111451-B2 | Mercaptoazole derivatives as lubricating additives | THE LUBRIZOL CORPORATION (US) | 2021-09-07 | — | — | US | disclosed |
| US-20190153349-A1 | MERCAPTOAZOLE DERIVATIVES AS LUBRICATING ADDITIVES | THE LUBRIZOL CORPORATION | 2019-05-23 | — | — | US | disclosed |