Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022863 | 0.94 | ALDH1A1 (0.41) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL21022667 | 0.81 | CREBBP (0.49) | TDP1ALDH1A1MAPK1HSD17B10RECQL | |
| SCHEMBL8030664 | 0.73 | DRD2 (0.52) | ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL23880033 | 0.73 | SLC9A1 (0.53) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL9628527 | 0.73 | ALDH1A1 (0.35) | CYP3A4ALDH1A1CA2HSD17B10HTT | |
| SCHEMBL23880031 | 0.73 | CYP3A4 (0.57) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| Toluene SCHEMBL29287380 | 0.71 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL19024893 | 0.70 | CYP3A4 (0.64) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL44320 | 0.70 | CYP3A4 (0.89) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL21605355 | 0.70 | CYP3A4 (0.59) | CYP3A4TSHRATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111451-B2 | Mercaptoazole derivatives as lubricating additives | THE LUBRIZOL CORPORATION (US) | 2021-09-07 | — | — | US | disclosed |
| US-20190153349-A1 | MERCAPTOAZOLE DERIVATIVES AS LUBRICATING ADDITIVES | THE LUBRIZOL CORPORATION | 2019-05-23 | — | — | US | disclosed |