SCHEMBL21022934

SCHEMBL21022934

NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.46
ALOX5 P09917 1/20 0.42
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM5A P29375 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
MC5R P33032 3/20 0.39
MC3R P41968 3/20 0.39
ACHE P22303 1/20 0.39
LTA4H P09960 1/20 0.39
MC4R P32245 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775331 0.87 L3MBTL1 (0.49) L3MBTL1
SCHEMBL10761433 0.85 L3MBTL1 (0.51) L3MBTL1MC5RMC3RMC4R
SCHEMBL9775314 0.82 L3MBTL1 (0.52) L3MBTL1MC5RMC3RMC4R
SCHEMBL9543318 0.82 L3MBTL1 (0.42) L3MBTL1ALOX5KDM4AKDM4CKDM5A
SCHEMBL8009232 0.82 PPIB (0.41) L3MBTL1ALOX5LTA4H
SCHEMBL9775278 0.81 KDM4A (0.52) L3MBTL1KDM4A
SCHEMBL23502347 0.81 HTT (0.50) L3MBTL1KDM4AKDM4C
SCHEMBL22211256 0.81 L3MBTL1 (0.47) L3MBTL1ALOX5KDM4AKDM4CKDM5A
SCHEMBL17109816 0.81 HTT (0.63)
SCHEMBL21023137 0.81 CYP3A4 (0.41) L3MBTL1ALOX5KDM4AKDM4CKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149046-B2 Antibacterial sideromycins Hsiri Therapeutics, Inc. (US) 2021-10-19 US disclosed
US-20190153010-A1 ANTIBACTERIAL SIDEROMYCINS Hsiri Therapeutics, LLC 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149046-B2 Antibacterial sideromycins SLC40A1, SFXN1, SLC39A14 L3MBTL1 1599/4885ALOX5 2537/4885KDM4A 3153/4885
US-20190153010-A1 ANTIBACTERIAL SIDEROMYCINS SLC40A1, SFXN1, SLC39A14 L3MBTL1 1599/4885ALOX5 2537/4885KDM4A 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.