Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18977395 | 0.70 | — | — | |
| SCHEMBL807629 | 0.68 | HTR3A (0.38) | HTR3AHTR2AHTR2CPDE4B | |
| SCHEMBL13093306 | 0.67 | HTR3A (0.37) | HTR3A | |
| SCHEMBL18408638 | 0.66 | DRD2 (0.47) | — | |
| SCHEMBL24504976 | 0.62 | HTR2A (0.35) | HTR2AHTR2C | |
| SCHEMBL21788702 | 0.62 | RAD52 (0.36) | HTR2AHTR2C | |
| SCHEMBL7719942 | 0.60 | — | — | |
| SCHEMBL13767655 | 0.59 | SLC18A3 (0.36) | HTR2C | |
| SCHEMBL6083553 | 0.59 | HTR3A (0.44) | HTR3AHTR2AHTR2CPDE4B | |
| SCHEMBL23182676 | 0.59 | DRD2 (0.36) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620428-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2019-05-22 | — | — | EP | disclosed |