Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022962 | 0.67 | HTR3A (0.36) | HTR3A | |
| SCHEMBL807629 | 0.62 | HTR3A (0.38) | HTR3A | |
| SCHEMBL20805968 | 0.62 | HTR3A (0.66) | HTR3AJAK3QDPR | |
| SCHEMBL6083553 | 0.60 | HTR3A (0.44) | HTR3AJAK3 | |
| SCHEMBL24504976 | 0.60 | HTR2A (0.35) | — | |
| SCHEMBL4530764 | 0.59 | CHRNB2 (0.47) | — | |
| SCHEMBL13901719 | 0.59 | — | — | |
| SCHEMBL13716501 | 0.59 | — | — | |
| SCHEMBL13093266 | 0.58 | QDPR (0.79) | HTR3AJAK3QDPR | |
| SCHEMBL5792003 | 0.58 | QDPR (0.79) | HTR3AJAK3QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123006-A1 | PYRROLIDINE COMPOUND | 武田薬品工業株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |