SCHEMBL21023339

SCHEMBL21023339

Cn1c2cc3c(=O)c4cccc(-c5cccs5)c4n(C)c3cc2c(=O)c2cccc(-c3cccs3)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.39
GSK3B P49841 1/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
PRKDC P78527 2/20 0.39
POLB P06746 2/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ATM Q13315 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.38
LTK P29376 1/20 0.38
CDK5 Q00535 1/20 0.38
MST1R Q04912 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
MET P08581 1/20 0.38
BAZ2B Q9UIF8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21023336 0.91 DPP4 (0.40) PRKCAGSK3BALDH1A1KDM4EPRKDC
SCHEMBL21023574 0.81 ALDH1A1 (0.43) ALDH1A1KDM4EPRKDCPOLBMEN1
SCHEMBL21023330 0.81 ATM (0.33) ALDH1A1KDM4EMEN1KMT2AATM
SCHEMBL21023478 0.78 BRD1 (0.38) ALDH1A1KDM4EPRKDCLMNAMEN1
SCHEMBL21023175 0.77 HSD17B10 (0.50) KDM4ELMNAKMT2AATMHSD17B10
SCHEMBL21023296 0.76 PRKDC (0.43) PRKCAALDH1A1PRKDCKMT2AATM
SCHEMBL21023179 0.75 BRD4 (0.46) ALDH1A1KDM4EPOLBLMNAMEN1
SCHEMBL21023288 0.75 MAOA (0.42) ALDH1A1KDM4EPOLBKMT2AATM
SCHEMBL17521791 0.75 ALDH1A1 (0.40) PRKCAGSK3BALDH1A1KDM4EPOLB
SCHEMBL21023476 0.74 BRD1 (0.46) PRKCAGSK3BALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190157350-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190157350-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND CRY1, CDH1, TEAD1 PRKCA 1732/4885GSK3B 3173/4885ALDH1A1 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.