Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319315 | 0.83 | NR3C1 (0.38) | MAPK14OXTRABHD16APPARAKDM5A | |
| SCHEMBL3316602 | 0.83 | MAPK14 (0.37) | MAPK14OXTRABHD16AMEN1KMT2A | |
| SCHEMBL4547931 | 0.82 | POLB (0.53) | MAPK14NPC1LMNARAB9APOLB | |
| SCHEMBL24185728 | 0.81 | POLB (0.36) | PPARAMEN1KMT2ANPC1LMNA | |
| SCHEMBL24878378 | 0.76 | ALDH1A1 (0.44) | MAPK14OXTRABHD16ANPC1LMNA | |
| SCHEMBL27678469 | 0.76 | MAPK14 (0.33) | MAPK14OXTRABHD16AKDM5AKDM4C | |
| SCHEMBL15779574 | 0.75 | OXTR (0.48) | OXTRABHD16AMEN1KMT2ANPC1 | |
| SCHEMBL31466379 | 0.72 | RXRA (0.39) | NOTUM | |
| SCHEMBL18161148 | 0.71 | PPARA (0.47) | PPARAMEN1KMT2ANPC1LMNA | |
| SCHEMBL1491089 | 0.71 | POLB (0.64) | MAPK14OXTRABHD16AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |