SCHEMBL21024709

SCHEMBL21024709

CCCCCCCCCCCCOC(=O)C(=O)c1ccc2c(c1)C(CCCC)(CCCC)c1cc(C(=O)c3ccccc3C)ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.41
▸ TSHR P16473 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ CYP3A4 P08684 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ PTPN11 Q06124 3/20 0.37
▸ ESR1 P03372 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ CCNB2 O95067 1/20 0.35
▸ CCNE2 O96020 1/20 0.35
▸ CDK1 P06493 1/20 0.35
▸ CCNB1 P14635 1/20 0.35
▸ CCNE1 P24864 1/20 0.35
▸ CDK2 P24941 1/20 0.35
▸ CCNB3 Q8WWL7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21025033 0.85 ALDH1A1 (0.43) ALDH1A1TSHRLMNACYP3A4TP53
SCHEMBL21168758 0.83 PDK2 (0.41) ALDH1A1HTT
SCHEMBL21183152 0.83 NAAA (0.38) ALDH1A1TSHRMAPK1L3MBTL1HTT
SCHEMBL21025038 0.81 ALDH1A1 (0.39) ALDH1A1TSHRLMNAPOLBL3MBTL1
SCHEMBL17084309 0.79 ALDH1A1 (0.36) ALDH1A1TSHRLMNAPTPN11NPC1
SCHEMBL21183191 0.79 PDK2 (0.34) ALDH1A1TSHRLMNACYP3A4TP53
SCHEMBL16477967 0.79 CNR2 (0.39) ALDH1A1TSHRLMNAPTPN11HTT
SCHEMBL17056226 0.78 ALDH1A1 (0.34) ALDH1A1TSHRLMNACYP3A4POLB
SCHEMBL21183150 0.77 PDK2 (0.34) ALDH1A1TSHRLMNAMAPK1HSD17B10
SCHEMBL17084351 0.77 ALDH1A1 (0.42) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885TSHR 3741/4885LMNA 268/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885TSHR 3741/4885LMNA 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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