SCHEMBL21025033

SCHEMBL21025033

CCCCCCCCCOC(=O)C(=O)c1ccc2c(c1)Cc1cc(C(=O)c3ccccc3C)ccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.43
▸ TSHR P16473 3/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TP53 P04637 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ GSTA1 P08263 2/20 0.39
▸ GSTP1 P09211 2/20 0.39
▸ PTPN11 Q06124 1/20 0.39
▸ SRD5A2 P31213 1/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ CNR2 P34972 2/20 0.37
▸ CCNB2 O95067 1/20 0.36
▸ CCNE2 O96020 1/20 0.36
▸ CDK1 P06493 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21025427 0.88 RAB9A (0.41) ALDH1A1TSHRLMNAPOLBSRD5A2
SCHEMBL21024709 0.85 ALDH1A1 (0.41) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL21025037 0.76 SRD5A2 (0.60) ALDH1A1TSHRCYP3A4KDM4EPOLB
Dimethylamine SCHEMBL8685908 0.75 TSHR (0.56) ALDH1A1TSHRLMNATP53CYP3A4
Water SCHEMBL27487586 0.75 TSHR (0.59) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL19935903 0.74 RAB9A (0.54) ALDH1A1LMNACYP3A4MAPK1KDM4E
SCHEMBL19936078 0.74 SRD5A2 (0.57) ALDH1A1CYP3A4KDM4EPOLBSRD5A2
SCHEMBL29851592 0.74 SRD5A2 (0.57) ALDH1A1CYP3A4KDM4EPOLBSRD5A2
SCHEMBL21025038 0.73 ALDH1A1 (0.39) ALDH1A1TSHRLMNAPOLBL3MBTL1
SCHEMBL21183194 0.73 RAB9A (0.46) ALDH1A1MAPK1SRD5A2TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885TSHR 3741/4885LMNA 268/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885TSHR 3741/4885LMNA 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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