Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093062 | 0.80 | MEN1 (0.51) | AKR1C3AKR1C2CLCN2MEN1KMT2A | |
| SCHEMBL31145465 | 0.80 | MEN1 (0.51) | AKR1C3AKR1C2CLCN2MEN1KMT2A | |
| SCHEMBL21027986 | 0.80 | AKR1C3 (0.43) | AKR1C3AKR1C2CLCN2MEN1KMT2A | |
| SCHEMBL30059145 | 0.74 | FABP4 (0.59) | MPOAKR1C3AKR1C2GRIK1PTGS1 | |
| SCHEMBL28418888 | 0.74 | FABP4 (0.59) | MPOAKR1C3AKR1C2GRIK1PTGS1 | |
| SCHEMBL11541557 | 0.74 | MPO (0.63) | MPOAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL7568727 | 0.70 | AKR1C3 (0.54) | AKR1C3AKR1C2MEN1KMT2APPARG | |
| SCHEMBL26895179 | 0.70 | RAPGEF4 (0.46) | P2RX1KCNJ6KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21625856 | 0.70 | KIF11 (0.54) | P2RX1KCNJ6KCNJ5KCNJ3HDAC3 | |
| SCHEMBL29514710 | 0.70 | KIF11 (0.54) | P2RX1KCNJ6KCNJ5KCNJ3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | Stingthera, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | SILICON SWAT, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | SILICON SWAT, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | MPO 1362/4885AKR1C3 2303/4885AKR1C2 2361/4885 |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | MPO 1362/4885AKR1C3 2303/4885AKR1C2 2361/4885 |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | STING1, IRF3, CGAS | MPO 1362/4885AKR1C3 2303/4885AKR1C2 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.