Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261330 | 0.84 | CNR2 (0.50) | CNR2CNR1POLBL3MBTL1CA12 | |
| SCHEMBL3024222 | 0.83 | CNR2 (0.49) | CNR2CNR1POLBL3MBTL1CA12 | |
| SCHEMBL16259593 | 0.81 | CNR2 (0.47) | CNR2CNR1POLBL3MBTL1CA12 | |
| SCHEMBL21028100 | 0.79 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL3692624 | 0.79 | CA12 (0.55) | CA12CA9 | |
| SCHEMBL3022552 | 0.71 | PGR (0.50) | CNR2 | |
| SCHEMBL3017636 | 0.71 | GLA (0.55) | CNR2CNR1 | |
| SCHEMBL27529773 | 0.71 | CA12 (0.57) | CNR2CNR1CA12CA9 | |
| SCHEMBL16259627 | 0.69 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL3691507 | 0.69 | MCL1 (0.52) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | CNR2 74/4885CNR1 68/4885POLB 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.