Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028137 | 0.82 | RORC (0.41) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16852479 | 0.81 | CYP2A13 (0.39) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL18077904 | 0.80 | RORC (0.39) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15536592 | 0.80 | RORC (0.39) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16849155 | 0.78 | RORC (0.39) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15560557 | 0.76 | RORC (0.37) | RORCALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6132960 | 0.70 | JAK2 (0.44) | ALDH1A1KDM4ELMNAGAAJAK2 | |
| SCHEMBL17709857 | 0.67 | CYP2A13 (0.38) | RORCALDH1A1LMNAMAPTJAK2 | |
| SCHEMBL11018891 | 0.66 | SIGMAR1 (0.47) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL21028170 | 0.65 | ALOX5AP (0.36) | ALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | RORC 3/4885ALDH1A1 671/4885KDM4E 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.