Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | S100A9 | P06702 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028122 | 0.89 | RORC (0.41) | RORCALDH1A1FFAR4S100A9KMT2A | |
| SCHEMBL21028212 | 0.86 | ALDH1A1 (0.39) | RORCALDH1A1KMT2AMEN1ALOX15 | |
| SCHEMBL16852355 | 0.85 | FFAR4 (0.42) | RORCALDH1A1FFAR4S100A9KMT2A | |
| SCHEMBL17709877 | 0.84 | ALDH1A1 (0.43) | RORCALDH1A1FFAR4S100A9KMT2A | |
| SCHEMBL17709875 | 0.84 | ALDH1A1 (0.43) | RORCALDH1A1FFAR4S100A9KMT2A | |
| SCHEMBL21026345 | 0.83 | RORC (0.42) | RORCALDH1A1FFAR4S100A9KMT2A | |
| SCHEMBL21026346 | 0.83 | PARG (0.46) | ALDH1A1KCNK3KCNK9FFAR4KMT2A | |
| SCHEMBL21028143 | 0.80 | RORC (0.41) | RORCALDH1A1NPSR1 | |
| SCHEMBL21028378 | 0.80 | RORC (0.45) | RORCNPSR1 | |
| SCHEMBL16849222 | 0.80 | ALDH1A1 (0.43) | RORCALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | RORC 3/4885ALDH1A1 671/4885KCNK3 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.