Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 18/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028389 | 0.86 | PTGS2 (0.40) | PTGS2PTGS1ALOX5 | |
| SCHEMBL15726921 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7143664 | 0.81 | PTGS2 (0.49) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7139884 | 0.79 | PTGS2 (0.63) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3582386 | 0.79 | PTGS2 (0.63) | PTGS2PTGS1ALOX5 | |
| SCHEMBL15723285 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3589022 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3584479 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3580212 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1ALOX5 | |
| SCHEMBL21241568 | 0.76 | HPN (0.55) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | PTGS2 2127/4885PTGS1 2042/4885ALOX5 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.