⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21029776 | 0.89 | — | — | |
| SCHEMBL21029881 | 0.83 | — | — | |
| SCHEMBL18513359 | 0.81 | NOD1 (0.34) | — | |
| SCHEMBL22844806 | 0.79 | CTSK (0.32) | — | |
| SCHEMBL19543400 | 0.79 | CTSK (0.32) | — | |
| SCHEMBL24786139 | 0.76 | LTA4H (0.32) | — | |
| SCHEMBL21262052 | 0.76 | C3AR1 (0.34) | — | |
| SCHEMBL21216105 | 0.74 | ACE (0.38) | — | |
| SCHEMBL20372778 | 0.71 | LTA4H (0.42) | — | |
| SCHEMBL24468878 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190160176-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-05-30 | — | — | US | disclosed |