⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513359 | 0.91 | NOD1 (0.34) | — | |
| SCHEMBL21029641 | 0.89 | — | — | |
| SCHEMBL24468878 | 0.79 | — | — | |
| SCHEMBL22844805 | 0.77 | — | — | |
| SCHEMBL278867 | 0.77 | — | — | |
| SCHEMBL21216105 | 0.76 | ACE (0.38) | — | |
| SCHEMBL21029881 | 0.76 | — | — | |
| SCHEMBL23685458 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL10308346 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL25773839 | 0.76 | MMP3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190160176-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-05-30 | — | — | US | disclosed |