Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082615 | 0.90 | POLA1 (0.46) | YTHDC1CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL29665047 | 0.81 | KDM4E (0.56) | YTHDC1CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL6283863 | 0.76 | POLA1 (0.69) | TP53POLA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL15720909 | 0.76 | POLA1 (0.69) | TP53POLA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8540848 | 0.76 | POLA1 (0.69) | TP53POLA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL23648123 | 0.76 | POLA1 (0.69) | TP53POLA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL1713327 | 0.76 | YTHDC1 (0.57) | YTHDC1CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL20240172 | 0.72 | HPGD (0.69) | TP53LMNA | |
| SCHEMBL20230464 | 0.71 | POLA1 (0.46) | KMT2AMEN1ALDH1A1POLA1KDM4E | |
| SCHEMBL21029537 | 0.70 | MEN1 (0.60) | YTHDC1CYP2C19KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971033-B1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | MODERNA THERAPEUTICS INC (US) | 2019-05-29 | — | — | EP | disclosed |