Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435011 | 0.80 | ALDH1A1 (0.44) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL10322765 | 0.80 | ALDH1A1 (0.44) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL14212000 | 0.72 | MAT2A (0.31) | — | |
| SCHEMBL9967742 | 0.72 | KCNH2 (0.51) | CYP1A2ALDH1A1LMNA | |
| SCHEMBL13104870 | 0.71 | SMN1; SMN2 (0.43) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL11340421 | 0.70 | ALDH1A1 (0.38) | CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL11340423 | 0.70 | ALDH1A1 (0.38) | CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL5413852 | 0.69 | CYP3A4 (0.36) | CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL20086552 | 0.69 | P2RX7 (0.42) | CYP3A4CYP1A2CYP2D6NFKB1ALDH1A1 | |
| SCHEMBL9967775 | 0.68 | CHAT (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178871-B2 | Herbicidal pyrimidine compounds | BASF SE (DE) | 2021-11-23 | — | — | US | disclosed |
| EP-3490985-B1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-20190159453-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11178871-B2 | Herbicidal pyrimidine compounds | DPYD, TYMP, TYMS | CYP3A4 909/4885CYP1A2 358/4885CYP2D6 196/4885 |
| US-20190159453-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | DPYD, TYMP, TYMS | CYP3A4 909/4885CYP1A2 358/4885CYP2D6 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.