Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038073 | 0.83 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL25065108 | 0.81 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL22197406 | 0.77 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL24874220 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL8517998 | 0.74 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL9850665 | 0.72 | — | — | |
| SCHEMBL18563486 | 0.72 | — | — | |
| SCHEMBL21104862 | 0.70 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2 | |
| SCHEMBL18559508 | 0.70 | TSHR (0.31) | TSHR | |
| SCHEMBL21646811 | 0.70 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464891-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190161445-A1 | Urea Derivative Or Pharmacologically Acceptable Salt Thereof | KYORIN SEIYAKU KK (JP) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464891-B2 | Urea derivative or pharmacologically acceptable salt thereof | FPR1, FPR2, FPR3 | TSHR 1014/4885ALDH1A1 2202/4885MAPK1 577/4885 |
| US-20190161445-A1 | Urea Derivative Or Pharmacologically Acceptable Salt Thereof | FPR1, FPR2, FPR3 | TSHR 1014/4885ALDH1A1 2202/4885MAPK1 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.