Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033033 | 1.00 | ALDH1A1 (0.43) | ALDH1A1PKMPOLBPSEN1PSEN2 | |
| SCHEMBL29512803 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PKMPOLBPSEN1PSEN2 | |
| SCHEMBL29287810 | 0.77 | ALDH1A1 (0.58) | ALDH1A1PKMPOLBPSEN1PSEN2 | |
| SCHEMBL8481506 | 0.75 | ALDH1A1 (0.44) | ALDH1A1PKMPOLBPSEN1PSEN2 | |
| SCHEMBL21032953 | 0.74 | HTR2A (0.45) | ALDH1A1MAPTKMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL10664262 | 0.73 | ALDH1A1 (0.43) | ALDH1A1PKMPOLBPSEN1PSEN2 | |
| SCHEMBL21032803 | 0.68 | ALDH1A1 (0.41) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21032959 | 0.68 | ALDH1A1 (0.41) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4399901 | 0.65 | PKM (0.41) | ALDH1A1PKMPOLBCYP2C9CYP2C19 | |
| SCHEMBL1336037 | 0.65 | LOX (0.60) | ALDH1A1PKMPOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |