Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032959 | 0.82 | ALDH1A1 (0.41) | HTR2AKCNH2HTR2CALDH1A1MMP8 | |
| SCHEMBL21032803 | 0.82 | ALDH1A1 (0.41) | HTR2AKCNH2HTR2CALDH1A1MMP8 | |
| SCHEMBL2048495 | 0.78 | HTR2A (0.59) | HTR2AKCNH2HTR2CMAPTAKR1C3 | |
| SCHEMBL7541817 | 0.74 | HTR2A (0.56) | HTR2AKCNH2HTR2CMAPTAKR1C3 | |
| SCHEMBL777971 | 0.74 | MAPT (0.56) | HTR2AKCNH2HTR2CMAPTAKR1C3 | |
| SCHEMBL21033418 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL21033033 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL21032801 | 0.74 | CA1 (0.49) | MAPTALDH1A1MMP8MMP13MMP1 | |
| SCHEMBL776895 | 0.72 | MAPT (0.55) | HTR2AKCNH2HTR2CMAPTALDH1A1 | |
| Cyanide SCHEMBL27638463 | 0.72 | HTR2A (0.54) | HTR2AKCNH2HTR2CMAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |