SCHEMBL21033710

SCHEMBL21033710

Ic1nc(-c2ccccc2)cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HPGD P15428 3/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ADORA3 P0DMS8 1/20 0.47
ACHE P22303 1/20 0.47
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
ADORA2A P29274 2/20 0.45
ADORA1 P30542 2/20 0.45
LMNA P02545 2/20 0.43
KDM4E B2RXH2 2/20 0.43
PDE10A Q9Y233 1/20 0.43
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
RAB9A P51151 1/20 0.41
AGTR1 P30556 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28256977 0.86 ALDH1A1 (0.50) SMN1; SMN2HPGDALDH1A1ACHEIDO1
SCHEMBL30616770 0.78 KDM4E (0.53) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL29446790 0.78 KDM4E (0.53) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL3318116 0.78 KDM4E (0.53) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL28880193 0.76 ADORA3 (0.51) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL786133 0.76 MEN1 (0.55) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL29177933 0.76 ACHE (0.52) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL696285 0.76 ACHE (0.56) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL31388225 0.76 MEN1 (0.55) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL6382426 0.76 IDO1 (0.54) MEN1KMT2ASMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10305041-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-28 US disclosed